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Department of Biochemistry

 
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Read more at: p53 impairs CRISPR/Cas9 in healthy cells
An artist's impression of DNA editing

p53 impairs CRISPR/Cas9 in healthy cells

The Taipale Group, and their collaborators, have published a new paper in Nature Medicine that may improve the efficiency of CRISPR in non-tumorigenic cells.


Read more at: A handful of transcription factors confer a hierarchical gene expression landscape
An artist's impression of a transcription factor binding to DNA

A handful of transcription factors confer a hierarchical gene expression landscape

The Taipale Group have published a new paper in Nature Biotechnology on the pattern of regulatory interactions involved in gene expression.


Read more at: DNA-targeting Molecules as Therapeutic Agents: a new book edited by Michael Waring
An artist's impression of DNA targeting by small molecules

DNA-targeting Molecules as Therapeutic Agents: a new book edited by Michael Waring

Professor Michael Waring has edited a new book, published by the Royal Society of Chemistry, entitled "DNA-targeting molecules as therapeutic agents".


Read more at: DNA binding mechanisms for promiscuous transcription factors
Surface representation of the HOXB13 transcription factor binding DNA

DNA binding mechanisms for promiscuous transcription factors

The Taipale Group have published a new research article in the journal eLife.


Read more at: Micro- and nano-structured electrodes increase current output in biological solar cells
A microporous electrode showing pores with a typical diameter of tens of nanometres populated by photosynthetic bacterial cells

Micro- and nano-structured electrodes increase current output in biological solar cells

The Howe Group and collaborators have published a new paper in Nature Communications.