Department of Biochemistry
Structural dynamics of modular polyketide synthases.
Molecular cell biology of trypanosomes.
The Wnt pathway in normal homeostasis and disease.
Plant cell wall synthesis and function.
Signalling to the actin cytoskeleton.
Molecular and cellular mechanisms of innate immunity.
Investigating the interactions of pathogenic bacteria with eukaryotic membranes
Chemical biology: from mechanism to droplet microfluidics (and back).
Biochemistry of photosynthetic organisms and their non-photosynthetic relatives.
Specificity, regulation and inhibition of protein-protein interactions in cellular signalling.
Sodium channels and other plasma membrane proteins.
Subcellular proteome and transcriptome.
Machinery of riboregulation and transport.
Characterisation of Cys-loop receptors.
Cell migration, actin dynamics and cancer metastasis
RNA transmission between organisms.
Genome-wide responses to stress.
Non-coding RNA, epigenetics and genome stability
Structure, dynamics and membrane interactions of small G proteins and their downstream effectors.
Integral membrane protein biology: structure, dynamics and function.
Small G protein-regulated signalling networks.
Molecular mechanisms of genomic stability.
The cell biology of obligate intracellular bacteria
Innovation in Teaching
Regulation of alternative pre-mRNA splicing.
Transcriptional control of growth.
Genetic interrogation of epigenetic pathways.
Cambridge Lactation Lab: Modelling human lactation to support long-term health
Investigating molecular function, diversity and evolution in cells.
Control of bacterial virulence and biofilm formation in the opportunistic human pathogen, Pseudomonas aeruginosa.
Cell size regulation and cell fate decisions.
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