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Department of Biochemistry

 
Jim Metcalfe

Transforming growth factor-beta signalling pathways.

 

Key publications

Kirschenlohr H, Ellis P, Hesketh R, Metcalfe J (2012). Gene expression profiles in white blood cells of volunteers exposed to a 50 Hz electromagnetic field. Radiat. Res., 178(3):138-149. doi: 10.1667/rr2859.1

Scollen S, Luccarini C, Baynes C, Driver K, Humphreys MK, Garcia-Closas M, Jonine F, Lissowska J, Pharoah PD, Easton DF, Hesketh R, Metcalfe JC, Dunning AM (2011). TGF-beta signaling pathway and breast cancer susceptibility. Cancer Epidemiol. Biomarkers Prev., 20(6):1112-1119. doi: 10.1158/1055-9965.EPI-11-0062

Oklü R, Hesketh R, Wicky S, Metcalfe JC (2011). Expression of mRNA isoforms of latent transforming growth factor-β binding protein-1 in coronary atherosclerosis and human tissues. Biochem. Genet., 49(3-4):213-225. doi: 10.1007/s10528-010-9400-x

Oklü R, Hesketh R, Wicky S, Metcalfe JC (2011). Localization of latent transforming growth factor-β binding protein-1 in human coronary atherosclerotic plaques. Circ. J., 75(1):196-200. doi: 10.1253/circj.cj-10-0334

Scollen S, Dunning AM, Bradshaw AC, Hesketh R, Metcalfe JC (2008). Association of gene variants in the TGF-beta signalling pathways with invasive breast cancer risk. Breast Cancer Res., 10(Suppl 2):P48. doi: 10.1186/bcr1932

Contact details

Research Group Leader  Jim Metcalfe

Email  jcm1000@cam.ac.uk

Opportunities

Jim Metcalfe is no longer able to accept enquiries from prospective students or staff; his laboratory has now closed.