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Department of Biochemistry

Read more at: Paul Dupree is a Highly Cited Researcher for 2024
Paul Dupree HCR

Paul Dupree is a Highly Cited Researcher for 2024

We are delighted that Paul Dupree is a Highly Cited Researcher again for 2024 . He has been selected for nine out of the last ten years since 2014. According to the selection criteria, each researcher receiving this prestigious award has:

'authored multiple Highly Cited Papers™ which rank in the top 1% by...


Read more at: George Salmond awarded the Marjory Stephenson Prize for 2025
George Salmond

George Salmond awarded the Marjory Stephenson Prize for 2025

Our emeritus professor, George Salmond has been awarded the Marjory Stephenson Prize for 2025 from the Microbiology Society . Professor Salmond spent his distinguished career studying the molecular genetics of cell division, developing genetic tools to control the growth of bacteria and working on the discovery, analysis...


Read more at: New paper shows translocons, and targeting peptides, for four membranes were directly inherited from haptophytes with a new plastid in dinoflagellates
Fig. 5A

New paper shows translocons, and targeting peptides, for four membranes were directly inherited from haptophytes with a new plastid in dinoflagellates

Ross Waller’s lab has published a paper, ‘ Plastid translocon recycling in dinoflagellates demonstrates the portability of complex plastids between hosts ’ in Current Biology in collaboration with colleagues in Ben Luisi’s lab and at the MRC Cambridge and the Cell and Plant Physiology Laboratory, Université Grenoble Alpes...


Read more at: Designing a Synthetic Biology Workbench: NED and the Magnificent Seven
Fig. 1: Basic properties of the S. cerevisiae MMNs under 6 different growth conditions. From: Minimisation of metabolic networks defines a new functional class of genes.

Designing a Synthetic Biology Workbench: NED and the Magnificent Seven

A paper in this week’s Nature Communications , by Prof Steve Oliver and former members of his lab, reports a major step toward improving the efficiency of industrial microbes. Generating a minimal metabolic network ( MMN ) should improve the production efficiency of engineered microbes by reducing their scope to divert the...



Read more at: Joshua Lawrence wins prizes for PhD research
Joshua Lawrence

Joshua Lawrence wins prizes for PhD research

Biochemistry PhD student Joshua Lawrence has received the Katharine Burr Blodgett Award for his doctoral research. This prize recognises outstanding work by a recent PhD graduate in the field of colloid and interface science. The prize is named in honour of Katharine Burr Blodgett, who was the first woman to receive a PhD...


Read more at: Translational funding awarded to advance novel cancer immunotherapy
T cells killing a tumour cell & LGR5 expression in colorectal cancer

Translational funding awarded to advance novel cancer immunotherapy

Joint funding from the Cambridge Enterprise Technology Investment Fund and Cancer Research Horizons has been awarded to researchers Marc de la Roche (Department of Biochemistry) and Maike de la Roche (Cancer Research UK Cambridge Institute).


Read more at: Claudia Bonfio awarded European Research Council Starting Grant
Claudia Bonfio

Claudia Bonfio awarded European Research Council Starting Grant

It is a great pleasure to announce that Claudia Bonfio has been awarded a European Research Council Starting Grant . She comes back to Cambridge from the University of Strasbourg to join the Department of Biochemistry as a research group leader, after previous postdoctoral positions here at the MRC Laboratory of Molecular...



Read more at: New technology enables faster response to disease outbreaks like COVID-19
Fig. 1: Workflow for high-throughput functional analysis of antibodies secreted by single cells.

New technology enables faster response to disease outbreaks like COVID-19

An article published in Nature Biotechnology by Katrin Fischer et al. from Florian Hollfelder ’s group in collaboration with the groups of James Thaventhiran , Marko Hyvonen , Nick Matheson and Charlotte Deane establishes a new, generalised technology for finding potentially therapeutic antibodies in response to infectious...


Read more at: A tale of two HUSH complexes: defending cells against invading retroelements
Graphical abstract from the article

A tale of two HUSH complexes: defending cells against invading retroelements

The HUSH complex preserves genome integrity through epigenetic silencing of invasive retroelements. A new study led by Josh Danac in the Tchasovnikarova lab now describes HUSH2, a related complex that instead represses interferon-stimulated genes. The cell exploits competition between HUSH and HUSH2 to couple retroelement...


Read more at: Hosting the next generation of scientists
Biochemistry ASTP Students 2024

Hosting the next generation of scientists

Today we say farewell to our first-ever A-level student group of aspiring scientists. We have really enjoyed hosting them this week to gain experience of lab work and research life in Biochemistry. More information about the ASTP programme is here .



Read more at: New article on how the Gallop Lab's research can help people with rare diseases
Adult African Clawed Frog. Photo: Xenbase.

New article on how the Gallop Lab's research can help people with rare diseases

A feature on the Cambridge University website explores the Gallop Lab's research on how the actin cytoskeleton is involved in changing the shape of cells and moving them around as an embryo develops into a fully-formed organism, and how frogs can help people with rare diseases.


Read more at: Biochemistry PhD student wins social impact award
Sam Hodder receives Vice-Chancellor’s Social Impact Award

Biochemistry PhD student wins social impact award

Congratulations to Sam Hodder, who has won the PhD Student Award for the 2024 Vice-Chancellor’s Social Impact Award ! During a clinical placement, Sam developed Chum, a platform using stories and games to educate children about their cancer and treatments.


Read more at: Opening the tightly linked grass cell wall polymer network leads to improved biomass properties
Reduction of xylan cross linking

Opening the tightly linked grass cell wall polymer network leads to improved biomass properties

The grass family provides staple foods for billions of people worldwide, feed for animals, and biomass for the production of bioenergy. Plant biomass is primarily composed of lignin and polysaccharides that crosslink and interact with each other, forming complex and tightly knit cell walls. These networks of wall...