Proteomics

Proteomics is the analysis of complete complements of proteins and includes not only their identification, but also quantitation, determination of cellular location, how they are modified, how they interact with each other, their activities and, ultimately, the elucidation of protein function. This powerful analysis can, for example, allow differences in the protein levels of samples between diseased and normal tissues to be assessed. Proteins are generally enzymatically digested (with or without pre-fractionation) to produce peptides which are then analysed by state-of-the-art mass spectrometry techniques.

The Cambridge Centre for Proteomics offers considerable expertise to worldwide researchers in industrial and academic environments in gel and mass spectrometry-based proteomics. Within the Centre, full quantitative analysis on virtually any sample of any complexity is possible, as well as customised analysis, such as for unusual sample types and novel protein modifications.