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Department of Biochemistry

 

2014 | 2013 | 2012 | 2010 | 2008 | 2007 | 2006 | 2005 |

before 2005

 
 
2014
[16] de la Roche, M., Ibrahim, A.E.K., Mieszczanek, J., Bienz, M. (2014) LEF1 and B9L shield beta-catenin from inactivation by Axin, desensitizing colorectal cancer cells to tankyrase inhibitors. Cancer research, 74 (5), 1495–1505. Abstract
 
2013
[15] Yang, Y., de la Roche, M., Crawley, S.W., Li, Z., Furmaniak-Kazmierczak, E., Cote, G.P. (2013) PakB binds to the SH3 domain of Dictyostelium Abp1 and regulates its effects on cell polarity and early development. Molecular biology of the cell, 24 (14), 2216–2227. Abstract
 
2012
[14] de la Roche, M., Rutherford, T.J., Gupta, D., Veprintsev, D.B., Saxty, B., Freund, S.M., Bienz, M. (2012) An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid. Nature communications, 3, 680. Abstract
[13] de la Roche, M., Tessier, S.N., Storey, K.B. (2012) Structural and functional properties of glycerol-3-phosphate dehydrogenase from a mammalian hibernator. The protein journal, 31 (2), 109–119. Abstract
 
2010
[12] Metcalfe, C., Ibrahim, A.E.K., Graeb, M., de la Roche, M., Schwarz-Romond, T., Fiedler, M., Winton, D.J., Corfield, A., Bienz, M. (2010) Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer. Cancer research, 70 (16), 6629–6638. Abstract
 
2008
[11] Mieszczanek, J., de la Roche, M., Bienz, M. (2008) A role of Pygopus as an anti-repressor in facilitating Wnt-dependent transcription. Proceedings of the National Academy of Sciences of the United States of America, 105 (49), 19324–19329. Abstract
[10]

de la Roche, M., Worm, J., Bienz, M. (2008) The function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells. BMC cancer, 8, 199. Abstract

 
2007
[9]

de la Roche, M. and Bienz, M. (2007) Wingless-independent association of Pygopus with dTCF target genes. Current biology : CB, 17 (6), 556–561. Abstract

2006
[8]

Crawley, S.W., de la Roche, M., Lee, S.-F., Li, Z., Chitayat, S., Smith, S.P., Cote, G.P. (2006) Identification and characterization of an 8-kDa light chain associated with Dictyostelium discoideum MyoB, a class I myosin. The Journal of biological chemistry, 281 (10), 6307–6315. Abstract

 
2005
[7] de la Roche, M., Mahasneh, A., Lee, S.-F., Rivero, F., Cote, G.P. (2005) Cellular distribution and functions of wild-type and constitutively activated Dictyostelium PakB. Molecular biology of the cell, 16 (1), 238–247. Abstract
   
before 2005
[6] de la Roche, M., Lee, S.-F., Cote, G.P. (2003) The Dictyostelium class I myosin, MyoD, contains a novel light chain that lacks high-affinity calcium-binding sites. The Biochemical journal, 374 (Pt 3), 697–705. Abstract
[5] de la Roche, M., Smith, J.L., Rico, M., Carrasco, S., Merida, I., Licate, L., Cote, G.P., Egelhoff, T.T. (2002) Dictyostelium discoideum has a single diacylglycerol kinase gene with similarity to mammalian theta isoforms. The Biochemical journal, 368 (Pt 3), 809–815. Abstract
[4] de la Roche, M., Smith, J.L., Betapudi, V., Egelhoff, T.T., Cote, G.P. (2002) Signaling pathways regulating Dictyostelium myosin II. Journal of muscle research and cell motility, 23 (7-8), 703–718. Abstract
[3] de la Roche, M. and Côté, G.P. (2001) Regulation of Dictyostelium Myosin I and II. Biochimica et Biophysica Acta (BBA) - General Subjects, 1525 (3), 245–261. Abstract
[2] Lee, S.-F., Mahasneh, A., de la Roche, M., Cote, G.P. (1998) Regulation of the p21-activated Kinase-relatedDictyostelium Myosin I Heavy Chain Kinase by Autophosphorylation, Acidic Phospholipids, and Ca2+-Calmodulin. Journal of Biological Chemistry, 273 (43), 27911–27917. Abstract
[1] de la Roche, M., Shen, Z., Byers, D.M. (1997) Hydrodynamic properties of Vibrio harveyi acyl carrier protein and its fatty-acylated derivatives. Archives of biochemistry and biophysics, 344 (1), 159–164. Abstract
   
   
   
   

 

 

 

Contact details

Research Group Leader  Marc de la Roche​

Email  mad58@cam.ac.uk

Location  Sanger Building

Opportunities

The de la Roche Group is accepting enquiries from prospective interns, undergraduate students, postgraduate students and postdoctoral researchers.