skip to content

 

Department of Biochemistry

 
Publications Blog
Read more at: New paper shows translocons, and targeting peptides, for four membranes were directly inherited from haptophytes with a new plastid in dinoflagellates
Fig. 5A

New paper shows translocons, and targeting peptides, for four membranes were directly inherited from haptophytes with a new plastid in dinoflagellates

Ross Waller’s lab has published a paper, ‘ Plastid translocon recycling in dinoflagellates demonstrates the portability of complex plastids between hosts ’ in Current Biology in collaboration with colleagues in Ben Luisi’s lab and at the MRC Cambridge and the Cell and Plant Physiology Laboratory, Université Grenoble...


Read more at: Designing a Synthetic Biology Workbench: NED and the Magnificent Seven
Fig. 1: Basic properties of the S. cerevisiae MMNs under 6 different growth conditions. From: Minimisation of metabolic networks defines a new functional class of genes.

Designing a Synthetic Biology Workbench: NED and the Magnificent Seven

A paper in this week’s Nature Communications , by Prof Steve Oliver and former members of his lab, reports a major step toward improving the efficiency of industrial microbes. Generating a minimal metabolic network ( MMN ) should improve the production efficiency of engineered microbes by reducing...


Read more at: New technology enables faster response to disease outbreaks like COVID-19
Fig. 1: Workflow for high-throughput functional analysis of antibodies secreted by single cells.

New technology enables faster response to disease outbreaks like COVID-19

An article published in Nature Biotechnology by Katrin Fischer et al. from Florian Hollfelder ’s group in collaboration with the groups of James Thaventhiran , Marko Hyvonen , Nick Matheson and Charlotte Deane establishes a new, generalised technology for finding potentially therapeutic antibodies in response...


Read more at: A tale of two HUSH complexes: defending cells against invading retroelements
Graphical abstract from the article

A tale of two HUSH complexes: defending cells against invading retroelements

The HUSH complex preserves genome integrity through epigenetic silencing of invasive retroelements. A new study led by Josh Danac in the Tchasovnikarova lab now describes HUSH2, a related complex that instead represses interferon-stimulated genes. The cell exploits competition between HUSH and HUSH2 to couple...


Read more at: Opening the tightly linked grass cell wall polymer network leads to improved biomass properties
Reduction of xylan cross linking

Opening the tightly linked grass cell wall polymer network leads to improved biomass properties

The grass family provides staple foods for billions of people worldwide, feed for animals, and biomass for the production of bioenergy. Plant biomass is primarily composed of lignin and polysaccharides that crosslink and interact with each other, forming complex and tightly knit cell walls. These networks of wall...