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The Department's buildings are currently open for wet laboratory work only. We have carried out a comprehensive COVID-19 risk assessment process and have introduced a number of new measures to ensure the safety of our staff, including reduced building occupancy, strict social distancing, 'family'-based working, and increased cleaning and hygiene regimes. All staff who can work remotely will do so for the foreseeable future. Please continue to contact us by email until further notice.

Department of Biochemistry

 

The Department has conducted a comprehensive COVID-19 risk assessment process and has introduced a number of new measures to ensure the safety of our staff. In order to accommodate these new measures, our facilities will be operating revised services for the foreseeable future. Details of current arrangements and available services can be found here.

Cryo-Electron Microscopy

Cryo-electron microscopy (Cryo-EM) is used to obtain images of the molecules and cells that form the machinery of life. Through imaging samples at atomic resolution via an electron beam, the resulting 3D reconstructions enable scientists to determine the architecture of proteins, biological molecules and their macromolecular complexes. This information provides insight and allows researchers to answer a range of questions relating to human health and the design of treatment for disease. Areas of particular interest for study include human DNA damage repair mechanisms, bacterial transport systems that export proteins and antibiotics out of the cell, and how cell signalling pathways are aberrant in tumours.

Funding received from the Wellcome Trust and the University of Cambridge has created this state-of-the-art Cryo-EM facility, with a unique tandem of both high-end Titan Krios 300kV and mid-range Talos Arctica 200kV cryo-electron microscopes.

Contact Details

Facility Manager: 

+44 (0)1223 761857

Technical Support: 

+44 (0)1223 333669

Location

Rooms 00.03-00.04, 00.07-00.08, 1.61
Sanger Building
Department of Biochemistry
University of Cambridge
80 Tennis Court Road
Cambridge
CB2 1GA

Office Hours

Monday-Friday: 09:00-17:00