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Department of Biochemistry

 
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Read more at: 'GPS-like' strategies in proteomics

'GPS-like' strategies in proteomics

Josie Christopher and Kathryn Lilley, along with 13 authors from world-leading subcellular proteomics laboratories, have published a comprehensive review in Nature Reviews Methods Primers covering the major techniques in the field.


Read more at: Unwinding the secrets of the coronavirus genome, loop by loop
Unwinding the secrets of the coronavirus genome, loop by loop.

Unwinding the secrets of the coronavirus genome, loop by loop

Omer Ziv, with the Miska Group and collaborators, has uncovered how the genome of SARS-CoV-2 uses genome origami to infect and replicate successfully inside host cells. This could inform development of effective drugs that target specific parts of the virus genome, in the fight against COVID-19.


Read more at: Green energy and better crops: tinted solar panels could boost farm incomes
Tinted solar panels fitted to a greenhouse roof.

Green energy and better crops: tinted solar panels could boost farm incomes

The Howe Group and their collaborators have demonstrated the use of tinted, semi-transparent solar panels to generate electricity and produce nutritionally-superior crops simultaneously, bringing the prospect of higher incomes for farmers and maximising use of agricultural land.


Read more at: Promoting translational frame-shifting to kill mycobacteria
Crystal structure of the AW7 compound occupying the active site of Mycobacterium abscessus TrmD enzyme.

Promoting translational frame-shifting to kill mycobacteria

The Blundell Group and their collaborators have published an article in Nucleic Acids Research identifying a new class of antibiotics against mycobacteria that target tRNA methylation.


Read more at: Switching on a key cancer gene could provide first curative treatment for heart disease
Adult mouse heart 48 hours after activation of Myc together with Ccnt1 expression.

Switching on a key cancer gene could provide first curative treatment for heart disease

The Evan Group and their collaborators have published a new paper in Nature Communications demonstrating that making the Myc gene overactive and functional in the hearts of mice can trigger heart cell regeneration.