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Department of Biochemistry

2D image showing double-stranded DNA (green) melting under tension to single-stranded DNA (blue).

We are pleased to announce that the Department has received delivery of the C-trap, a state-of-the-art, single-molecule instrument that was purchased thanks to the generous support of the BBSRC 19ALERT scheme.


The C-trap combines fluorescence microscopy, optical tweezers, and microfluidics to enable researchers to investigate the behaviour of biological systems at single-molecule level, with a high degree of resolution and mechanical control.

The instrument is now available to the Cambridge research community and we are looking forward to the unique scientific insights that its technology will provide. Interested users should contact Dr Luca Pellegrini and Dr Luay Joudeh.

The C-trap is the latest addition to join our set of biophysical tools, such as cryo-EM, that researchers in biochemistry routinely use in their ground-breaking research.


The Biotechnology and Biological Sciences Research Council (BBSRC) 19ALERT scheme supports eligible researchers in the purchase of mid-range research equipment for multi-user and multi-project use.


2D image showing double-stranded DNA (green) melting under tension to single-stranded DNA (blue).

Credit: LUMICKS.


Luca Pellegrini

Publication date

26 January 2021