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Department of Biochemistry

#Gproteins20 conference logo.

CANCELLED: Focused Meeting,
6-9 July 2020,
Victoria Gallery and Museum, Liverpool.


As a precautionary measure against coronavirus, please note that the upcoming "Small G proteins in cellular signalling and disease" conference has been cancelled.

We apologise to any delegates that were hoping to attend.


Small G proteins of the Ras superfamily regulate a plethora of cell signalling pathways and impact on most biological processes. Deregulation of these proteins and their pathways often results in disease, such as cancer and genetic disorders, and plays a role in infection by pathogenic organisms. The founding member of this superfamily of proteins, Ras, drives ~20% of human cancers and its inhibition is a goal of global importance.

In this meeting we will discuss research covering all five families of small G proteins, to generate new ideas, collaborations and scientific strategies from diverse inputs. This will include the Ras family, involved in cell growth, the Rho family, which drive cytoskeletal rearrangements, the Arf and Rab families, which play a role in vesicle trafficking, and Ran, which is responsible for nuclear transport.

This conference will gather renowned experts to highlight recent advances in understanding the molecular mechanisms of small G protein function. The programme is designed to bring together leaders in the field and younger scientists, providing a platform for early stage investigators to present their latest research while accommodating ample opportunities for networking.

Sessions at the meeting will cover the most exciting, cutting edge topics in small G protein signalling:

  • Small G proteins in disease: challenges and progress,
  • Post-translational modifications, localisation and compartmentalisation,
  • Small G protein function in context,
  • Regulators and modulators,
  • Downstream signalling,
  • Systems analysis of small G protein networks.


Programme coordinators

  • Darerca Owen
  • Helen Mott
  • Ian Prior


#Gproteins20 conference logo.

Credit: Darerca Owen and Helen Mott, Department of Biochemistry, University of Cambridge.


Darerca Owen and Helen Mott

Publication date

6 March 2020