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Paula MacGregor

The molecular basis and evolution of host-parasite interactions in African trypanosomes

There are multiple species of African trypanosome that can each infect multiple mammalian hosts. Together they are the causative agents of both human and animal African trypanosomiasis, with bovine trypanosomiasis acting as a major constraint to cattle farming across sub-Saharan Africa.

I am interested in the molecular and cell biology of the interaction between African trypanosomes and their external environment in the mammalian host. Current work in the lab aims to experimentally characterise molecular diversity of the cell surfaces amongst different African trypanosome species and how that affects host-parasite interactions.

Work in the lab is funded by a BBSRC David Phillips Fellowship (May 2017 – Feb 2023)


Current Lab Members

Dr Nicola Moloney (Postdoctoral research associate)

Alice McDowell (BBSRC PhD student)


Previous Lab Members

Laura Rustarazo Calvo (Erasmus+ Intern)


Contact Details

Dr Paula MacGregor
Department of Biochemistry
University of Cambridge
Tennis Court Road


Twitter: @MacGregor_Lab