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Paula MacGregor

The molecular basis and evolution of host-parasite interactions in African trypanosomes

There are multiple species of African trypanosome that can each infect multiple mammalian hosts. Together they are the causative agents of both human and animal African trypanosomiasis, with bovine trypanosomiasis acting as a major constraint to cattle farming across sub-Saharan Africa.

I am interested in the molecular and cell biology of the interaction between African trypanosomes and their external environment in the mammalian host. Current work in the lab aims to experimentally characterise molecular diversity of the cell surfaces amongst different African trypanosome species and how that affects host-parasite interactions.

Work in the lab is funded by a BBSRC David Phillips Fellowship (May 2017 – May 2022)


Joining the lab

If you are interested in joining the lab either as a post-doctoral fellow or as a postgraduate student then I am always happy to consider your application. Please send your CV with the names of two referees, a brief description of your research experience and the reasons behind your application. If there are funded positions available then they will be advertised. If not, then you must also consider how you will obtain funding.

I will shortly be advertising a BBSRC-funded 4-year PhD studentship to start in Oct 2018. The studentship will cover a stipend at the standard Research Council rate (£14,553 per annum for 2017/18), research costs and tuition fees at the UK/EU rate, and is available for UK and EEA students who meet the UK residency requirements. The successful student will carry out their PhD in my group but will also take part in the Cambridge BBSRC DTP programme training courses, events and internship. 

One MRC-funded PhD project is also currently available (from Oct 2018) through the Cambridge MRC DTP Programme:


Contact Details

Dr Paula MacGregor
Department of Biochemistry
University of Cambridge
Tennis Court Road