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Small G proteins in cellular signalling and disease

last modified May 23, 2018 12:58 PM
Focused Meeting, 9-12 July 2018, Clare College, Cambridge, UK.

Small G proteins regulate a plethora of cell signalling pathways, thus impacting on most biological processes. As a result of their broad spread cellular influence, the deregulation of these proteins and their pathways often results in disease, especially cancer.

The interest, both academic and commercial, in these proteins has always been intense, but with the instigation of the Ras Initiative by the NCI in 2013, interest is newly invigorated. Hopes are high that new ways being developed will successfully target cancers driven by mutant Ras.

Sessions during this focused meeting will include:

  • Therapeutic targeting of small G proteins,
  • Localisation: spatiotemporal signalling,
  • Small G protein function in context,
  • Regulators and modulators,
  • Effector signalling pathways,
  • Small G proteins in disease: challenges and progress.

For more information, and to register, visit Further information is also available on the Facebook event page.


Programme Coordinators:

Darerca Owen

Helen Mott



Register here.



#GProteins18 Conference Logo.

Credit: Darerca Owen and Helen Mott, Department of Biochemistry, University of Cambridge


Darerca Owen and Helen Mott

Publication Date

13 February 2018