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The Department's buildings are currently open for wet laboratory work only. We have carried out a comprehensive COVID-19 risk assessment process and have introduced a number of new measures to ensure the safety of our staff, including reduced building occupancy, strict social distancing, 'family'-based working, and increased cleaning and hygiene regimes. All staff who can work remotely will do so for the foreseeable future. Please continue to contact us by email until further notice.

Department of Biochemistry


Remkes Scheele

PhD student
Joined the lab: June 2017
Background and Current Projects: During my Masters in Molecular Biology and Biotechnology at the University of Groningen, I was involved in two major research projects. The first was in the group of Prof. Roelfes in Groningen, where I created a new artificial metalloenzyme by genetically incorporating hydroxyquinoline-alanine in the hydrophobic pocket of an otherwise non-catalytically active transcription factor. The hydroxyquinoline side chain was coupled with several metal complexes, capable of catalysing two biotransformations. The other project was in the group of Prof. Arnold, where I build on the efforts of previous students to develop a biocatalytic platform to produce β-branched tryptophan derivatives from cheap achiral substrates.
As a PhD student in the Hollfelder group, I hope to gain a more fundamental understanding of structure-function relationships in enzymes. Furthermore I would like to use directed evolution on mammalian protein kinases to assist in drug development against several types of cancer associated with upregulated MAPK pathways.
Interests: Movies, travelling, and speciality beers.


Remkes Scheele 

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