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Hollfelder group

Wolfgang Koch

PhD student
Joined the lab: April 2017
Background and Current Projects: I studied Food Science and Biotechnology at the University of Natural Resources and Life Sciences Vienna and received my BSc in 2013. In course of my bachelor’s thesis in the group of Prof. Florian Rüker I worked on the cloning, screening and characterization of novel antibody fragments, so called Fcabs (Fc antigen binding). After a 3 month placement in the group of Prof. Julia Vorholt at ETH Zurich (Switzerland), were I worked on enhanced expression of encoded enzymes for introduction of methylotrophy in E. coli, I continued my MSc in Biotechnology in Vienna, which included a semester abroad at the University of Georgia, USA. In course of my master’s thesis in the group of Prof. Andreas Plückthun at the University of Zurich, I worked on the characterization and affinity maturation of DARPins binding the oncofetal receptor human ROR1. After receiving my MSc, I joined the group of Prof. Florian Hollfelder for my PhD studies in collaboration with MedImmune, funded by the EU Marie Skłodowska-Curie training network ES-Cat. My project aims for a modular drug discovery platform for novel protease based drugs that combine a protease activity with a substrate binding moiety.
Interests: I highly enjoy travelling as well as a wide variety of sports.



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