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Evan Group - Tania Campos

Tania Campos

Position: Research Associate

Background:

I have always been motivated to study the mechanisms underpinning cancer, because it is the second cause of death in the world and it poses fascinating questions about biological systems. This abiding interest is reflected by my scientific career. I studied Bioengineering, then gained a Master’s in Biochemistry and Bioinformatics and a Ph.D. in Biological Science at the University of Concepcion. My thesis work on signal transduction area was addressed using cell-based cancer models but, useful though these are, I became increasingly aware of the greater validity of in vivo models, which more closely mimic the complex nature of cancers. Because of this, I chose Professor Gerard Evan’s laboratory for my next step in pursuit my career goals, joining the laboratory in July 2016. 

Publications:

  • Evan GI, Hah N, Littlewood TD, Sodir NM, Campos T, Downes M, Evans RM. “Re-engineering the Pancreas Tumor Microenvironment: A "Regenerative Program" Hacked”. Clin Cancer Res. 23(7):1647-1655. 2017.
  • Campos T, Ziehe J, Fuentes-Villalobos F, Riquelme O, Peña D, Troncoso R, Lavandero S, Morin V, Pincheira R, Castro AF. "Rapamycin requires AMPK activity and p27 expression for promoting autophagy-dependent Tsc2-null cell survival". Biochim Biophys Acta. 1863(6 Pt A):1200-7. 2016.
  • Campos T, Ziehe J, Palma M, Escobar D, Tapia J, Pincheira R, Castro AF. “Rheb promotes cancer cell survival through p27Kip1-dependent activation of autophagy”. Mol Carcinog. 55(2):220-9. 2016.
  • Armijo ME*, Campos T*, Fuentes-Villalobos F, Palma ME, Pincheira R, Castro AF. "Rheb signaling and tumorigenesis: mTORC1 and new horizons". International Journal of Cancer. Int J Cancer. 15;138(8):1815-23 (*AME and CT contributed equally to this work). 2016.
  • Escobar D, Hepp M, Farkas C, Campos T, Sodir N, Morales M, Alvarez C, Swigart L, Evan G, Gutiérrez L, Nishinakamura R, Castro AF, Pincheira R. “Sall2 is required for pro-apoptotic Noxa expression and genotoxic stress-induced apoptosis by doxorubicin”. Cell Death Dis. 6:e1816.doi: 10.1038/cddis. 2015.
  • Castro AF, Campos T, Babcock JT, Armijo ME, Martínez-Conde A, Pincheira R, Quilliam LA. “M-Ras induces Ral and JNK activation to regulate MEK/ERK-independent gene expression in MCF-7 breast cancer cells”. J Cell Biochem. 113(4):1253-64. 2012. 
  • Maldonado-Agurto R, Toro G, Fuentealba J, Arriagada C, Campos T, Albistur M, Henriquez JP, Olate J, Hinrichs MV, Torrejón M. “Cloning and spatiotemporal expression of RIC-8 in Xenopus embryogenesis”. Gene Expr Patterns. 11(7):401-8. 2011.

Updated: September 2017.