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Research Group Leaders

These pages describe the research undertaken in each group and are maintained by the groups themselves.

 

Tom Blundell

Structural biology, bioinformatics and drug discovery

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Kevin Brindle

Molecular imaging in cancer

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Bill Broadhurst

Structural dynamics of modular polyketide synthases

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Guy Brown

Neuroinflammation, mitochondria and cell death

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Mark Carrington

Molecular cell biology of trypanosomes

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Marc de la Roche

Oncogenic Wnt signaling in cancer

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Paul Dupree

The extracellular matrix in plants - understanding cell wall biosynthesis

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Gerard Evan

Determining the molecular basis of cancer

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Richard Farndale

Collagen receptors and collagen-binding proteins

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Jasmin Fisher

Executable Biology

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Jenny Gallop

Membrane-triggered actin polymerization: molecular mechanisms and morphogensis

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Nick Gay

Structrual biology of cellular signalling by Toll/Interleukin 1 transmembrane receptors

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Andrew Grace

Molecular pathophysiology of cardiac arrhythmias

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Jules Griffin

Lipid profiling and signalling

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Brian Hendrich

Transcriptional control of stem cell fate

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Florian Hollfelder

Mechanism in Chemistry and Biology

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Chris Howe

Biochemistry of photosynthesis; molecular evolution of photosynthetic microorganisms and Plasmodium

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Marko Hyvönen

Specificity, regulation and inhibition of protein-protein interactions in cellular signalling

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Richard Jackson

Mechanisms of Translation Initiation Site Selection on Eukaryotic Cellular and Viral mRNA

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Steve Jackson

Maintenance of genome stability

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Tony Jackson

Ion channels and plasma membrane proteins

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Stephanie Jung

Platelet collagen receptor GPVI-dimer a specific target in ischaemic heart disease and stroke

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Svetlana Khoronenkova

DNA repair and neurodegenerative diseases

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Ernest Laue

Structural studies of chromatin assembly/disassembly

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Peter Leadlay

Molecular assembly lines and combinatorial biosynthesis

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Kathryn Lilley

Cambridge Centre for Proteomics

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Trevor Littlewood

Oncogenic signalling in cancer

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Rick Livesey

Mammalian neural stem cell biology, fundamental and applied

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James Locke

Quantitative understanding of how cells respond to environmental signals

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Ben Luisi

Crystallographic and functional studies of regulatory assemblies

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Sarah Lummis

Molecular characterization of neurotransmitter-gated ion channels

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Juan Mata

Posttranscriptional regulatory networks

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Helen Mott

Structural biology of small G proteins and their downstream effectors

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Daniel Nietlispach

Integral membrane proteins: structure, dynamics and function

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Ellen Nisbet

Molecular evolution - from algae to malaria

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Steve Oliver

Functional genomics and systems biology

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Darerca Owen

G proteins and their effectors as therapeutic targets in invasion and metastasis

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Luca Pellegrini

Macromolecular mechanisms of genome duplication and stability

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Markus Ralser

The regulatory function of the metablic network

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Nick Robinson

Coordinating DNA repair and chromosomal replication

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George Salmond

Molecular microbiology: bacterial quorum sensing, virulence,
protein secretion, antibiotic regulation, gas vesicles and flotation, toxin-antitoin systems and bacetiophage abortive infection

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Dee Scadden

Investigating the fate of hyper-edited dsRNA

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José Silva

Biology of induced pluripotency

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Austin Smith

Embryo stem cell biology

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Chris Smith

Regulation of alternative pre-mRNA splicing

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Nancy Standart

Post-transcriptional regulation of gene expression

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Jean Thomas

Chromatin and gene regulatory proteins

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Ross Waller

Cell evolution - novel chromatin biology, remodelling of the cytoskeleton for parasitism, and organellogenesis in diverse eukaryotes

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Martin Welch

Regulation of Virulence and Biofilm formation by Pathogenic Bacteria

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Simone Weyand

Membrane protein structure, function and cellular activities

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Philip Zegerman

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Nianshu Zhang

Regulation of stress response and chronological ageing

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Recent members

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