We are pleased to welcome several new members of staff. Marc de la Roche joins us as a University Lecturer, having been working at the MRC LMB. He will be working on oncogenic Wnt signaling in cancer. Jasmin Fisher, who was already associated with the Cambridge Systems Biology Centre and teaching in the Part III course, takes up a 20% position as University Reader. She will retain her position with Microsoft Research and her research programme in executable biology. We will also shortly be joined by another new University Lecturer Ross Waller, who is currently in Melbourne and works on eukaryotic diversity and evolution. Simone Weyand takes up a Royal Society/Wellcome Trust Henry Dale Fellowship to work on structure/function relationships and mode of action of G-protein-coupled receptors. We also welcome Peter Martin in our accounts section, Agnieszka Marcyniuk as a technician and Beryl Purcell in research grants administration.