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Discovery of new structure of cell’s communication channel could aid drug development

last modified Apr 28, 2014 01:48 PM

Tony Jackson's group, working with colleagues in the Department's X-Ray Crystallographic and Biophysics facilities and in the Department of Pharmacology, have published a paper in Journal of Biological Chemistry "Crystal Structure and Molecular Imaging of the Nav Channel β3 Subunit Indicates a Trimeric Assembly". They hope their discovery will lead to improvements in drugs that act on the sodium channel to treat a range of cardiac and pain conditions. For the full story see the main University news web site.