skip to primary navigationskip to content

Hollfelder Group

Chemical Biology: From Mechanism to Droplet Microfluidics (and Back)

Nature has evolved the most amazing functional biomolecules and we want to know how they work. Enzymes are the all-purpose catalysts that make the Chemistry of Life run smoothly and efficiently, under the mildest, ‘greenest’ conditions – and protein binders are involved in governing many biological processes.

The Hollfelder group is interested in gaining a fundamental understanding of the principles responsible for molecular recognition processes in chemistry and biology. We probe whether these principles enable us to describe, manipulate and ultimately make functional molecules. Using an eclectic mix of techniques we extend the mechanistic lessons learned to potential applications in biotechnology, synthetic chemistry and medicine.

Moonlighting molecules: finding new uses for old enzymes (Urbach et al., 2015, Chemistry & Biology)

Read more

Contact details


Dr Florian Hollfelder

Tel: +44 (0)1223 766048


Mailing address:

Department of Biochemistry
University of Cambridge
80 Tennis Court Road


Visiting address:

Sanger Building, Old Addenbrookes Site