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Vacancies in the Department

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Dec 05, 2014.

Proteomics: KAUST funded post doctoral research position

Subcellular proteomics in apicomplexan parasites, and the role of a novel family of mitochondrial RNA-binding proteins

Skill sets: Mass spectrometry, quantitation, proteomics.

A position is available for a post-doctoral research worker to apply state-of-the-art technologies to determine subcellular proteomes in apicomplexan parasite Toxoplasma gondii. High-resolution spatial and temporal proteome maps will be developed by extended versions of Localisation of the Organelle Proteomics using Isotope Tagging (LOPIT). A novel family of mitochondrial RNA-binding proteins has recently been identified and implicated in the specialization of apicomplexans as parasites. The location, behavior and molecular interactions of these proteins will be a particular focus of this work in order to better understand their significance in this devastating group of parasites.

The project is a collaboration with: Professor Kathryn Lilley at the Cambridge Centre for Proteomics (), Department of Biochemistry, University of Cambridge; Dr Ross Waller at the Department of Biochemistry, University of Cambridge; and Associate Professor Arnab Pain at King Abdullah University of Science and Technology, Saudi Arabia. The position will be based in Cambridge.

Candidate should have a PhD in mass spectrometry and quantitative proteomics and also have a good knowledge of cell biology and 'omics informatics pipelines.

CCP is a state of the art proteomics laboratory with Orbitrap, QTof equipped with IMS, Triple ToF and triple quadrupole mass spectrometers. It has a history of developing quantitative proteomics methodologies and also creating proteomics software and developing novel statistical approaches to the analysis of quantitative data.

The position is available from 1st March 2015 and is funded through an alliance between the University of Cambridge and at King Abdullah University of Science and Technology.

Fixed-term: The funds for this post are available for 24 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For all enquiries please contact Stephanie Morley - personnel@bioc.cam.ac.uk or call on 01223 333617

Please quote reference PH04902 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Dec 05, 2014.

Proteomics: KAUST funded post doctoral research position

Molecular characterization of the role of RNA-binding proteins (RBPs) in Arabidopsis thaliana drought responses

Skill sets: Mass spectrometry, quantitation, phosphoproteomics, RNA biology

A position is available for a post-doctoral research worker to apply state-of-the-art technologies to identify and characterize RNA-binding proteins (RBPs) as well as the bound RNA species that have a role in plant stress responses and responses to water-stress (drought) in particular. We are interested in obtaining insights into plant RBP profiles and the mechanism of action of RBPs. The emphasis will be on whether or not RBPs are themselves subject to functionalization through post-translational modifications such as stimulus specific phosphorylation or methionine oxidation. We hypothesize that RBPs have a key role in abiotic stress responses and may therefore make promising novel targets for transgenic interventions to increase drought tolerance.

The project is a collaboration with Professor Kathryn Lilley's group at the Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge and Professor Christopher Gehring at King Abdullah University of Science and Technology, Saudi Arabia, but will be based in Cambridge.

Candidate should have a PhD in mass spectrometry and quantitative proteomics and also have a good knowledge of RNA and cell biology and 'omics informatics pipelines.

CCP is a state of the art proteomics laboratory with Orbitrap, QTof equipped with IMS, Triple ToF and triple quadrupole mass spectrometers. It has a history of developing quantitative proteomics methodologies and also creating proteomics software and developing novel statistical approaches to the analysis of quantitative data.

The position is available from 1st March 2015, and is funded through an alliance between the University of Cambridge and at King Abdullah University of Science and Technology.

Fixed-term: The funds for this post are available for 18 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For all enquiries please contact Stephanie Morley - personnel@bioc.cam.ac.uk or call on 01223 333617

Please quote reference PH04901 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate/Senior Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Dec 18, 2014.

Post-doctoral synthetic (peptide) Chemist

A post-doctoral Research Associate/Senior Research Associate position is available to work on the design and synthesis of biologically-active peptides, to support and extend the use of the Collagen Toolkits peptides (http://collagentoolkit.bio.cam.ac.uk), and for uses including the construction of cell-reactive biomaterial scaffolds. The post is based in Department of Biochemistry, Tennis Court Road, Central Cambridge in Professor Richard Farndale's laboratory, and is for 6 months initially, funded by a Wellcome Trust Biomedical Resource Grant. There is the possibility of extension for another 3 years, depending on the success of grant renewals currently in progress. The level of appointment will depend upon skills and experience.

The successful applicant will be qualified in synthetic organic chemistry, and have a strong interest in applied protein chemistry. He or she will be fully trained and have significant experience in solid-phase peptide synthesis. Microwave technology for peptide synthesis will be very useful, although training will be provided if necessary.

Candidates should have a PhD in a relevant biological or chemical science or the equivalent.

Closing date: 20 Jan 2015. Interviews are anticipated during January/early February.

Fixed-term: The funds for this post are available for 6 months in the first instance with the possibility of renewal for up to September 2018.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please direct any enquiries to Personnel - personnel@bioc.cam.ac.uk

Please quote reference PH04993 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.