skip to primary navigationskip to content

Vacancies in the Department

Apprentice Laboratory Technician (Fixed Term)

From Jobs at the University of Cambridge. Published on May 18, 2015.

An Apprentice Laboratory Technician is required to work in the University of Cambridge, Department of Biochemistry. The successful applicant will undertake a structured training programme rotating through a number of laboratories over the three year apprenticeship to provide technical support for the Department's research, teaching and infrastructure. You will assist both researchers and classroom staff with basic laboratory duties including operation of laboratory equipment and preparation of working solutions for experiments.

The successful applicant will be passionate about science and technology and will be required to undertake an appropriate day-release course at NVQ Level 2 and Level 3. Ideally you will be computer literate, able to communicate effectively, enthusiastic, have the ability to express clearly technical details and show evidence of practical problem-solving skills.

Skills required include the ability to concentrate for extended periods, good manual dexterity and the ability to learn quickly.

Applicants should hold or be expected to achieve GCSEs at Grade C or above (or equivalent) in Mathematics, English and a science-based subject as a minimum.

Fixed-term: The funds for this post are available for up to 3 years in the first instance.

To apply for this vacancy please visit: https://goo.gl/eCWEWB This will take to the role on the National Apprentice website, you will then be able to apply on-line.

For all informal enquiries please email Debra Manning - dam24@cam.ac.uk.

Please quote reference PH06127 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Chief Research Laboratory Technician

From Jobs at the University of Cambridge. Published on May 22, 2015.

Applications are invited for a chief research laboratory technician to support projects within the laboratories of Professor Sir Tom Blundell and Professor Ben Luisi. The role holder is primarily concerned with the management and smooth running of these two large research groups in the department, both working in the field of Structural Biology. The role holder has responsibilities for the Biophysics and Crystallographic X-Ray facilities. For more information please visit the Professor Sir Tom Blundell and Professor Ben Luisi group webpages using the links below:

http://www.bioc.cam.ac.uk/people/uto/blundell

http://www.bioc.cam.ac.uk/people/uto/luisi

The role holder will act as the main point of day-to-day contact for all group members in the laboratories and is responsible for support to a diverse personnel including post-docs, Erasmus and Marie Curie students, Ph.D. and M.Phil students, 3rd and 4th year undergraduates and visitors. The role holder will convene, minute and chair regular group meetings concerning general laboratory matters, organisation and safety and ensure agreed actions are followed up.

The role is responsible for all purchasing for the groups and will maintain comprehensive records and analyses of purchasing trends. The role holder also manages the groups' research grants and ledger accounts and will be able to balance budgets and liaise with accounts teams to resolve anomalies. Assisting the group heads with grant proposals is a further requirement.

Ensuring the laboratories are in good order with regular checks for a safe working environment is paramount and the role holder will ensure the laboratories operate safely and in accordance with the Department and University Health and Safety Rules and guidance. They will maintain and review all safety records, laboratory documentation and chemical databases.

The role holder will carry out first line maintenance and training for new users on equipment used by the research groups. They will arrange repairs and assist with demonstrations and will assist facility managers of the Biophysics and Crystallographic X-Ray by preparing invoices and checking and re-charging equipment usage for these areas.

Skills and qualifications required: a relevant degree with significant laboratory management exposure. Knowledge of a range relevant equipment and the ability to provide first line support together with good IT skills. Strong communication skills, the ability to work as part of a team and carry out a number of versatile tasks as required, ability to work to deadlines and attention to details. Previous experience in a biological background would be advantageous.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made to Debra Manning - dam24@cam.ac.uk

Please quote reference PH06164 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Post-doctoral Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on May 01, 2015.

Post-doctoral Research Associate in Microbiology

A Post-doctoral Research Associate position is available to work on regulation of the glyoxylate shunt in the opportunistic human pathogen, Pseudomonas aeruginosa. The post is based in University of Cambridge, Department of Biochemistry, Central Cambridge working in the laboratory of Dr Martin Welch, and is funded by the BBSRC.

The successful applicant will ideally have experience in protein chemistry, enzymology and molecular microbiology. In addition experience in 13C flux analysis and a working knowledge of Python programming are desirable but not essential, as training will be provided if necessary.

The successful applicant will investigate the enzymology (kinetic/structural properties and regulation) of the TCA cycle/glyoxylate shunt branchpoint in P. aeruginosa. The enzymology of this metabolic branchpoint differs significantly from that in the well-characterized organism, Escherichia coli. Moreover, recent work has shown that flux through the glyoxylate shunt controls the activity of the major virulence determinant in P. aeruginosa; the Type III Secretion (T3S) System. In collaboration with colleagues in the United States, the accrued kinetic data will be used to populate a predictive flux model of the TCA cycle/glyoxylate shunt, with a view to identifying "nodes" that can be targeted to reduce flux through the shunt. Techniques include: microarray analyses and/or RNA-Seq, protein purification and characterization, kinetic analyses, [13C] flux analyses, protein phosphorylation ([32P]) assays, biophysical analyses, Westerns, in silico modelling and virulence assays (T3S).

The ideal candidate will have a PhD or has recently submitted for a PhD in a relevant science.

Interviews are anticipated during June.

Fixed-term: The funds for this post are available for 3 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made to Martin Welch - mw240@cam.ac.uk

Please quote reference PH06006 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Assistant[Temporary Cover] (Maternity Cover)

From Jobs at the University of Cambridge. Published on May 11, 2015.

Applicants are invited for a Research Assistant position working in the laboratory of Dr Marko Hyvonen in the University of Cambridge, Department of Biochemistry, Central Cambridge. The post holder will support the research in the Hyvonen group both in the general laboratory management (ordering, stock keeping) and by assisting postdoctoral fellows in their research projects.

A successful applicant is expected to have previous experience in modern molecular biology techniques, including DNA cloning, microbiology, protein expression and/or protein purification. Experience in laboratory management is desired. The applicant is expected to be have good interpersonal skills, to be helpful and collaborative in research group environment and to be able to work carefully and independently towards set goals in a timely manner.

The successful candidate will be educated to first degree level.

Maternity cover: This post is fixed-term for 6 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries can be addressed to Dr Hyvonen by email - mh256@cam.ac.uk

Please quote reference PH06066 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on May 15, 2015.

Applications are invited for a postdoctoral research associate position in Dr Juan Mata's laboratory in the Department of Biochemistry, University of Cambridge, Central Cambridge to work on the following BBSRC-funded project: 'Role of RNA-binding proteins in the control of RNA turnover: a genome-wide approach'. The project will use fission yeast as a model system to study how RNA decay is coordinated at the level of the whole cell, and will involve functional genomics approaches, biochemical methods and bioinformatics. More information on the laboratory can be found at http://www.bioc.cam.ac.uk/uto/mata.html.

Applicants should hold or have recently submitted for a PhD in a relevant subject, such as Genetics, Molecular Biology or Biochemistry. Direct experience with fission yeast or high throughput methods such as RNA-seq would be an advantage, but is not absolutely required. Funding will be available from 1st September 2015 for up to 9 months.

Fixed-term: The funds for this post are available for up to 9 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For informal enquiries please email Juan Mata - jm593@cam.ac.uk.

Please quote reference PH06104 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on May 19, 2015.

New drug targets for TB through prediction/investigation of impact of resistance mutations

Applications are invited for a post-doctoral research associate position that will form part of the Cambridge cohort of MM4TB, the EU FP7 collaboration in Tuberculosis.

The post holder will work in the laboratory of Professor Sir Tom Blundell in the University of Cambridge, Department of Biochemistry, Central Cambridge, working collaboratively with partners and to advise on the use of Credo, a database of protein-ligand interactions, and Chopin, our database of the M. tuberculosis structural proteome. The post-holder will also take the lead in rewriting the computer program SDM, which uses statistical analyses of amino acid substitutions in proteins of known structure to analyse the impacts of polymorphisms identified by gene sequencing. The post-holder will also collaborate with colleagues to integrate the computer program with mCSM which uses machine learning for analyses of effects of polymorphisms on protein stability, protein-protein, protein-nucleic acid, and protein-ligand interactions.

The successful applicant should have a proven knowledge of computer programming languages and should have written computer code for structural bioinformatics in the past.

Applicants should have a PhD in structural bioinformatics or computational biology or the equivalent with knowledge of molecular and structural biology.

Fixed-term: The funds for this post are available for 6 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Enquiries should be directed to Professor Sir Tom Blundell, tlb20@cam.ac.uk

Please quote reference PH06072 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate in Bioinformatics for Mass Spectrometry (Fixed Term)

From Jobs at the University of Cambridge. Published on May 21, 2015.

Postdoctoral positions in lipidomics and metabolomics

A postdoctoral research associate position is available for up to three years (12 months in the first instance) to work in the laboratory of Dr J.L. Griffin, University of Cambridge, Department of Biochemistry, Tennis Court Road, Cambridge. The project will develop tools to measure lipid species in conjunction with ion mobility, an exciting development in mass spectrometry which will allow the separation of ions according to their cross sectional area as well as their mass to charge ratio. It is envisaged that the successful candidate will work alongside an experienced mass spectrometrist involved in method development, whilst developing new software tools for processing the data obtained.

We are looking for an bioinformatician with experience in processing biological mass spectrometry data or other relevant experience such as experience in signal processing. The work is a collaborative project between Dr. J.L Griffin (Dept of Biochemistry), Prof. Michael Wakelam (Babraham Institute) and Agilent technology. As part of this project the research associate will have access to a state of the art ion mobility Q-ToF LC-MS to develop new tools for lipidomics, and building on our work in diabetes and metabolic diseases (Griffin) and cancer (Wakelam) use the instrument to explore cellular signalling in these disease processes. Some examples of this work can be found in Roberts LD et al., Lancet Endocrinology, 2014; Roberts LD et al., Methods in Enzymology, 2014; Zhang Q & Wakelam MJ, Adv Biol Regul 2014.

Skills required are bioinformatics for metabolomics or proteomics and a general interest in metabolism and disease processes in mammals Previous work in metabolomics and/or lipidomics would be an advantage but we will consider relevant experience in other areas such as aspects of signal processing

Applicants should have a PhD or are about to submit or have the equivalent in a relevant science.

Fixed-term: The funds for this post are available for 12 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made to Dr J.L Griffin - jules.griffin@mrc-hnr.cam.ac.uk

Please quote reference PH06024 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate in Mass Spectrometry (Fixed Term)

From Jobs at the University of Cambridge. Published on May 01, 2015.

Postdoctoral Research Associate position in lipidomics and metabolomics

A postdoctoral research associate position is available for up to three years (12 months in the first instance) to work in the laboratory of Dr J.L. Griffin, University of Cambridge, Department of Biochemistry, Tennis Court Road, Central Cambridge. The project will develop tools to measure lipid species in conjunction with ion mobility, an exciting development in mass spectrometry which will allow the separation of ions according to their cross sectional area as well as their mass to charge ratio. As an experienced mass spectrometrist involved in method development, you will be expected to work alongside a bioinformatician who will develop new software tools for processing the data obtained.

We are looking for an experienced mass spectrometrist, ideally with some background in metabolomics and/or lipidomics. The work is a collaborative project between Dr. J.L Griffin (Dept of Biochemistry), Prof. Michael Wakelam (Babraham Institute) and Agilent technology. As part of this project the successful candidate will have access to a state of the art ion mobility Q-ToF LC-MS to develop new tools for lipidomics, and building on our work in diabetes and metabolic diseases (Griffin) and cancer (Wakelam) use the instrument to explore cellular signalling in these disease processes. Some examples of this work can be found in Roberts LD et al., Lancet Endocrinology, 2014; Roberts LD et al., Methods in Enzymology, 2014; Zhang Q & Wakelam MJ, Adv Biol Regul 2014.

Skills required in mass spectrometry and a general interest in metabolism and disease processes in mammals. Previous work in metabolomics and/or lipidomics would be an advantage.

Applicants should have a PhD or the equivalent in a relevant science.

Fixed-term: The funds for this post are available for 12 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal inquiries can be made to Dr J.L Griffin - jules.griffin@mrc-hnr.cam.ac.uk

Please quote reference PH06004 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.