skip to primary navigationskip to content

Vacancies in the Department

Bioinformatician (Fixed Term)

From Jobs at the University of Cambridge. Published on Jul 17, 2017.

Cambridge Centre for Proteomics is currently looking to recruit an experienced post-doctoral bioinformatician within its core facility unit.

The successful candidate will be required to analyse high-throughput proteomics datasets using numerous proteomic software packages (e.g. Proteome Discover, Scaffold and Mascot) and apply multiple statistical tests to datasets. Programming literacy (preferably R) is essential as is previous knowledge of working with proteomics data. The role will require the research and development of analysis solutions to complex biological problems. The role-holder will be an integral member of CCP and will need to interact closely with other members of CCP and internal and external users of the service to provide interpretation of results from complex datasets and also experimental design.

The role holder will have a PhD in bioinformatics, biochemistry or a related subject.

Fixed-term: The funds for this post are available for 36 months in the first instance.

Informal enquiries about the position can be sent to Mike Deery (md289@cam.ac.uk)

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Enquiries about the online application process can be sent to Adriana Dote (personnel@bioc.cam.ac.uk)

Please quote reference PH12438 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Expression of Interest, Early Career Researchers Fellowship

From Jobs at the University of Cambridge. Published on Jul 20, 2017.

Potential Research Fellows

The Department of Biochemistry in Cambridge is seeking to host early career researchers who have the ambition to start an independent research group with an external fellowship.

The Department has more than 40 research groups (bioc.cam.ac.uk/research) with interests that fall broadly into the following areas:

  • Chemical biology and drug design
  • Disease biology
  • DNA and chromatin biology
  • Molecular microbiology
  • Plant biochemistry and bioenergy
  • RNA biology
  • Signalling and trafficking
  • Systems biology

We offer a dynamic environment where research benefits from state of the art facilities for structural biology, bioinformatics, biophysics, Cryo-EM, protein analysis, biological mass spectrometry and DNA sequencing with complementary facilities housed in neighbouring departments and institutes within the School of Biological Sciences.

If you are interested in obtaining the Department's support for your application, you should first discuss your research ideas with a relevant departmental group leader. You can view a list of all departmental group leaders and their research on the Department's website: http://www.bioc.cam.ac.uk/people/uto

To make an application, please email fellows@bioc.cam.ac.uk by 15th September 2017 with the following:

  • A CV including a list of publications (highlighting the three publications that you consider to be most significant)
  • Two references sent directly to fellows@bioc.cam.ac.uk
  • A two page outline of your intended research programme
  • A statement of why you would like to work in the Department
  • A brief outline of the facilities you would need during a Fellowship

Applications from women and ethnic minorities are particularly welcome.

Informal enquiries can also be sent to: fellows@bioc.cam.ac.uk

Shortlisted applicants will be informed by 1st October 2017 and invited to visit the department and give a seminar on either 10th or 17th October 2017. There will be further opportunities to apply in 2018 if this timetable does not suit your personal circumstances.

Successful candidates will be offered support for the preparation of their Fellowship application. If you are interested in other schemes please contact fellows@bioc.cam.ac.uk

Typical fellowship schemes:

  • Wellcome Trust Sir Henry Dale Fellowship
  • Medical Research Council Career Development Award
  • Biotechnology and Biological Sciences Research Council David Phillips Fellowships Cancer Research UK Career Development Fellowship
  • Royal Society University Research Fellowship
  • Royal Society Dorothy Hodgkin Fellowship

For individuals returning to research after a career break:

  • Wellcome Trust Career Re-entry Fellowship
  • Daphne Jackson Fellowship

Please quote reference PH12837 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jun 29, 2017.

Postdoc in Ultrahigh-throughput Exploration of Metagenomic Libraries

A postdoctoral position is available for 12 months (with a possibility of extension) to work with Florian Hollfelder on ultrahigh-throughput exploration of metagenomics libraries. Metagenomes comprise enormous reservoirs coding for proteins with useful activities, but harvesting this potential is difficult, because useful candidates are rare and hidden in an overwhelming majority of irrelevant genes. Traditionally screening campaigns of metagenomic libraries thus have required massive capital-expenditure for robotic systems and much manpower, making them expensive, slow and available to very few users.

We have just shown (Colin et al. Nature Communications 2015, 6:10008. doi: 10.1038/ncomms10008) that exploration and exploitation of the metagenome is accelerated and made more successful by ultrahigh-throughput screening in picoliter droplets: allowing throughput of tens of millions of assays per hour, at dramatically lower cost (and work!) per assay. We now want to use this platform technology to identify enzymes for biosynthesis of therapeutic small molecules, for green bioenergy conversion, bioremediation, food chemistry and other industrial applications. The postdoc project involves establishment of suitable assays for these tasks in microdroplet format, building environmental metagenomics libraries and looking for new catalysts that are then characterised mechanistically and structurally.

Candidates with a background (and published track record) in protein engineering, mechanistic enzymology, organic synthesis and microfluidic engineering are especially welcome. The work is part of the EU Project 'Metafluidics' that involves collaborations with companies and academic groups in Spain, Denmark, Norway, France, Portugal and the UK.

Fixed-term: The funds for this post are available for 12 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For informal enquires about this position please contact Florian Hollfelder (fh111@cam.ac.uk)

Enquiries about the online application process can be sent to Adriana Dote (personnel@bioc.cam.ac.uk)

Please quote reference PH12610 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jul 12, 2017.

Combining 3D single molecule/super-resolution imaging with 3D genome structure determination to study nuclear architecture

Applications are invited for a postdoctoral Research Associate to work on a collaborative Wellcome Trust-funded research project between the Departments of Biochemistry, Chemistry and the Stem Cell Institute in Cambridge, focused on understanding mammalian interphase genome structure in mouse ES cells.

The aim of the project is to develop a highly efficient approach to combine 3D single molecule/super-resolution imaging with 3D genome structure determination of the same single mouse embryonic stem cell (see Stevens et al., Nature, 2017, 544, 59-64). This will be used to study factors affecting chromosome/genome structure and how this changes during differentiation.

We are seeking a highly motivated researcher with a PhD (or who expects to obtain one shortly), and expertise in either single molecule/super resolution imaging, single cell experiments or computational biology, who would like to work as part of a highly interdisciplinary team of biologists, chemists and mathematicians. For further details please contact either: Brian Hendrich (Brian.Hendrich@cscr.cam.ac.uk), Dave Klenerman (dk10012@cam.ac.uk) or Ernest Laue (e.d.laue@bioc.cam.ac.uk).

Fixed-term: This post is available for 12 months in the first instance, with a possibility of longer term funding.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Enquiries about the online application process can be sent to Adriana Dote (personnel@bioc.cam.ac.uk)

Please quote reference PH12751 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jul 12, 2017.

Development of genetic experimental tools in marine parasite Perkinsus

Skill sets: Molecular biology, cell biology, transformation technologies, cell culture, bioinformatics.

A post-doctoral position is available to develop and extend transformation technologies in Perkinsus. This genus consists of several important pathogens of marine shellfish, and is also a close relative and evolutionary model for apicomplexan parasites and dinoflagellate algae. The project will develop and extend existing transformation systems in Perkinsus including using CRISPR/Cas9-mediated genome engineering. This project will be based in the University of Cambridge, Department of Biochemistry, Tennis Court Road, Central Cambridge and is a collaboration between Dr Ross Waller (University of Cambridge), Dr Sebastian Gornik (National University of Ireland Galway), Professor Arnab Pain (King Abdullah University of Science and Technology, Saudi Arabia) and Professor Chris Howe (University of Cambridge). The project is also supported by a research assistant.

Candidates should have a PhD in molecular biology and have experience with eukaryotic transformation systems, preferably in eukaryotic algal or parasite systems. Experience with fluorescence microscopy and FACS will be an advantage, as well as a track record of publishing in high quality journals. Ability to work both as part of a team, and independently, coupled with excellent communication, organizational and problem solving skills are required.

The position is available from September 2017, and is funded for 2 years in the first instance.

Informal inquiries can be made by contacting Ross Waller (rfw26@cam.ac.uk).

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Enquiries about the online application process can be sent to Adriana Dote (personnel@bioc.cam.ac.uk)

Please quote reference PH12759 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jun 26, 2017.

Applications are invited for a Postdoctoral Research Associate to join the group of Dr Paula MacGregor within the Department of Biochemistry, University of Cambridge. The aim of the group's research is to improve our understanding of the molecular mechanisms that underlie the interactions between African trypanosomes and their mammalian hosts. This project will assess proteome diversity between African trypanosome species and will involve collaboration with other groups within the Department.

We are seeking a highly motivated researcher with a PhD (or who expects to obtain one shortly) in a relevant subject, with a strong background in biochemistry. Applications from individuals with experience in proteomics, computer programming and/or analysis of large data sets are particularly encouraged. Previous experience with parasite cell culture would be an advantage but is not essential.

The successful applicant will have the drive and ability to work independently as well as part of a team. The primary responsibilities of the role include developing and carrying out research objectives, preparing data for publication or presentation and training of students.

This full-time fixed-term post funded by the BBSRC for 2.5 years in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For informal enquires about this position please contact Dr Paula MacGregor pm560@cam.ac.uk

Enquiries about the online application process can be sent to Adriana Dote (personnel@bioc.cam.ac.uk)

Please quote reference PH12519 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jul 14, 2017.

Post-doctoral Research Associate - Genome-wide approaches to study translation (Fixed Term)

Applications are invited for a post-doctoral Research Associate position to be based in the University of Cambridge, Department of Biochemistry, central Cambridge, working in the laboratory of Dr Juan Mata. The post is funded by the BBSRC, UK.

The project will address the regulation of translation during stress responses, using the fission yeast Schizosaccharomyces pombe as a model system. The work will involve genome-wide approaches such as RNA-sequencing and ribosome profiling.

The successful candidate will have a PhD in Genetics, Biochemistry, or a related field. Expertise in RNA research (especially translation), high throughput approaches to study gene expression, and fission yeast genetics, will be advantageous but are not absolutely required.

The interviews are expected to take place in September.

The post will be available from 1st October 2017, and is funded for up to 20 months.

Informal enquires can be made by contacting Dr Juan Mata, email: jm593@cam.ac.uk; further information on the Mata lab can be obtained at http://www.bioc.cam.ac.uk/people/uto/mata.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Enquiries about the online application process can be sent to Adriana Dote (personnel@bioc.cam.ac.uk)

Please quote reference PH12780 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Senior Photographic Technician

From Jobs at the University of Cambridge. Published on Jun 28, 2017.

Applications are invited for the post or Photographic Technician in the Department of Biochemistry.

You will join a busy team that provides a comprehensive photographic/reprographic service to members of the Department and others within the School of Biological Sciences, often working to tight deadlines.

The successful applicant will be customer focussed with excellent communication and interpersonal skills. He/she should have some experience or training in a photographic/illustrative field with a basic knowledge of digital photography and image manipulation. The ability to support event photography would be beneficial. You will also be involved with the smooth running and operation of AV equipment in the Lecture Theatres and Meeting Rooms located within both Biochemistry buildings. Other activities will include the creation of ID cards, poster printing, plus student document printing and binding.

For informal enquires about this position please contact Chris Green (ccg23@cam.ac.uk)

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Enquiries about the online application process can be sent to Adriana Dote (personnel@bioc.cam.ac.uk)

Please quote reference PH12608 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Senior Research Technician (Fixed Term)

From Jobs at the University of Cambridge. Published on Jul 14, 2017.

The Waller laboratory based in the University of Cambridge, Department of Biochemistry is looking to recruit a Senior Research Technician.

The position will support a research project investigating the cell biology of apicomplexan parasite Toxoplasma gondii. This project entails screening large numbers of parasite proteins for cell location and function. The technician will assemble, prepare and quality control new expression, knockdown and knockout DNA constructs, transfect and clone the new parasite cell lines and prepare media and other reagents required for this project. The technician will also be trained to assist with preliminary screening of new transfectant lines, by immunofluorescence assay, Western blotting and genomic PCR, where their time allows.

Key duties: - cell culture of human and parasite cell lines - prepare media and other chemical reagents - basic assembly of DNA constructs including PCR, plasmid DNA purification and sequencing - assist with parasite transformation and primary analysis of these new cell lines.

The successful candidate should have a HNC level qualification or equivalent experience. Experience with Toxoplasma culturing and transfection, Golden Gate cloning methods, and fluorescence microscopy will be a strong advantage.

Fixed-term: The funds for this post are available for up to 12 months in the first instance.

For all informal inquiries, please contact Dr Ross Waller - rfw26@cam.ac.uk

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Enquiries about the online application process can be sent to Adriana Dote (personnel@bioc.cam.ac.uk)

Please quote reference PH12778 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Teaching Laboratory Technician (Fixed Term)

From Jobs at the University of Cambridge. Published on Jul 14, 2017.

A Teaching Laboratory Technician is required to join a small team servicing undergraduate practical classes in the Department of Biochemistry. During University term time the role assists in the preparation of reagents and equipment allocation for classes, setting out of teaching materials, ensuring equipment is in good working order and answering student enquiries. Out of term it is anticipated that the role holder will support external events held within the department and/or provide support to research labs.

This requires a conscientious, accurate and methodical approach and the ability to work to deadlines, sometimes under pressure. Manual dexterity and good communication and IT skills are essential as well as the ability to function efficiently in a small team.

Ideally you will have studied to A Level/ BTEC or equivalent in Chemistry or Biology although applicants educated to GCSE level in relevant subjects and with experience in molecular biology and biochemical techniques will also be considered for this role. Previous experience in a laboratory environment would be advantageous.

This is a full-time position initially funded for one year.

Informal inquiries about the role can be made by contacting Sio Ball - slrb2@cam.ac.uk

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Enquiries about the online application process can be sent to Adriana Dote (personnel@bioc.cam.ac.uk)

Please quote reference PH12779 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.